The Brimstone Society - a secretive cabal of occult scholars and military chaplains - have long sought out the services of mercenaries and private investigators in their mission to keep the world safe from the ongoing threat of vampires and demons. In searching for new talent, they discover Tony Redgrave of the demon-infested heartland of Limbo City. With a potential Apocalypse brewing in his own hometown, Brimstone sends their must lethal asset - the Dhampir known only as Agent BloodRayne - to recruit this troubled young hell-raiser and put his uniquely devilish gifts to good use before a literal Devil breaks loose on Earth.