A century after World War III left the planet a nuclear wasteland, earth is nearly unrecognizable. Alien 'Benefactors' have taken control of North America's most populous cities and built indomitable walls around them, defending their inhabitants but trapping them under a totalitarian rule. Outside these citadels, chaos reigns, led by the mutants of the wasteland; cultists, raiders, and canibal clans.

Glory, a rogue android, is roaming the wastes after escaping her sadistic "father". Alone and reeling from the effects of a previously sheltered life, her only ray of hope is Reza City, built upon the ruins of what used to be Phoenix, Arizona. True, the Benefactors have a strict ban on self-aware artificial intelligence in place, but that should only prove an issue if they realize she's an AI.

The real problem is what lurks outside the city: over a million square miles of harsh, unyielding desert. And slinking between the dunes and the fissures are the mutants, looking for an easy victim.